Stage-Specific Serum Proteomic Signatures Reveal Early Biomarkers and Molecular Pathways in Huntington’s Disease Progression

Background: Huntington’s Disease (HD) is a monogenic neurodegenerative disease resulting in a CAG repeat expansion in the <i>HTT</i> gene. Despite this genetic simplicity, its molecular mechanisms remain highly complex. Methods: In this study, untargeted serum proteomics, bioinformatics analysis, bi...

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Principais autores:	Christiana C. Christodoulou, Christiana A. Demetriou, Eleni Zamba-Papanicolaou
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2025-08-01
coleção:	Cells
Assuntos:	Huntington’s Disease proteomics serum analysis proteins bioinformatics pathway analysis
Acesso em linha:	https://www.mdpi.com/2073-4409/14/15/1195
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