Systematic druggable genome-wide Mendelian randomization identifies therapeutic targets for osteoporosis

Objectives: The aim of this study was to find potential drug targets of osteoporosis (OP) through systematic druggable genome-wide Mendelian randomization (MR) analysis. Methods: Combining the multi-omics data, we utilized drug target MR and mediation MR to search for potential drug targets of OP an...

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Detalhes bibliográficos

Principais autores:	Chiyun Sun, Ruikang Liu, Jiaming Hu, Weiming Fan, Chuanrui Sun, Pengcheng Shan, Xu Wei
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-06-01
Colecção:	Osteoporosis and Sarcopenia
Assuntos:	Druggable genes Mendelian randomization Osteoporosis Drug target Multi-omics
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2405525525000342
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