Cannabidiol inhibits TGF-β1-induced epithelial-mesenchymal transition in human conjunctival epithelial cells by interrupting TGF-β/Smad signaling

Abstract Epithelial-mesenchymal transition (EMT) plays a significant role in conjunctival fibrosis-related pathologies and has emerged as a promising therapeutic target for managing conjunctival fibrosis. Cannabidiol (CBD), a predominant non-psychoactive cannabinoid derived from the cannabis plant,...

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Bibliografiske detaljer

Principais autores:	Anil Baskan, Ezzat M. Awad, Ava Elahi, Javeria Pervaiz, Talin Barisani-Asenbauer
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Portfolio 2025-11-01
Serier:	Scientific Reports
Fag:	Epithelial-mesenchymal transition Conjunctival fibrosis Cannabidiol TGF-β signaling Smad pathway Interleukin-6
Online adgang:	https://doi.org/10.1038/s41598-025-25216-9
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