The Role of the Transcription Factor Nuclear Factor-kappa B in Thyroid Autoimmunity and Cancer

Nuclear factor-kappa B (NF-κB) is a ubiquitous transcription factor that is involved in inflammatory and immune responses, as well as in regulation of expression of many other genes related to cell survival, proliferation, and differentiation. In mammals, NF-κB comprises five subunits that can bind...

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Главные авторы:	Cesidio Giuliani, Ines Bucci, Giorgio Napolitano
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2018-08-01
Серии:	Frontiers in Endocrinology
Предметы:	NF-κB thyroid autoimmunity thyroid cancer transcription factors gene regulation major histocompatibility complex
Online-ссылка:	https://www.frontiersin.org/article/10.3389/fendo.2018.00471/full
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