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In silico investigation of acyclovir derivatives potency against herpes simplex virus

Herpes simplex virus (HSV) is a major human pathogen, sub-divided into two types: HSV-1 which causes oral and perioral infections and HSV-2 which causes genital herpes. The global disease burden is high with 67% and 11% of the World's population being infected with HSV-1 and HSV-2 respectively. Acyc...

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Principais autores: Clive M. Nyaribo, Florence A. Ng'ong'a, Steven G. Nyanjom
פורמט: Artigo
שפה:Inglês
יצא לאור: Elsevier 2023-03-01
סדרה:Scientific African
נושאים:
Computer aided drug design
Network pharmacology
Molecular docking
Acyclovir derivatives
Herpes simplex virus
גישה מקוונת:http://www.sciencedirect.com/science/article/pii/S2468227622003660
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