N4BP1 functions as a dimerization-dependent linear ubiquitin reader which regulates TNF signalling

Abstract Signalling through TNFR1 modulates proinflammatory gene transcription and programmed cell death, and its impairment causes autoimmune diseases and cancer. NEDD4-binding protein 1 (N4BP1) is a critical suppressor of proinflammatory cytokine production that acts as a regulator of innate immun...

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Detalhes bibliográficos

Principais autores:	Katarzyna W. Kliza, Wei Song, Irene Pinzuti, Simone Schaubeck, Simone Kunzelmann, David Kuntin, Arianna Fornili, Alessandro Pandini, Kay Hofmann, James A. Garnett, Benjamin Stieglitz, Koraljka Husnjak
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2024-04-01
Colecção:	Cell Death Discovery
Acesso em linha:	https://doi.org/10.1038/s41420-024-01913-8
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