Lung injury promoted by strong inspiratory efforts and breath stacking: impact of ventilation mode

Abstract Background Breath stacking, particularly double triggering, is a common patient–ventilator asynchrony during strong inspiratory effort. It can cause excessive tidal volumes and high transpulmonary pressures, contributing to ventilator-induced lung injury (VILI). The mode-specific consequenc...

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Autori principali:	Yasuhiro Norisue, Sunao Usami, Yukie Ito, Muneyuki Takeuchi, Atsushi Kawamura, Ryuichi Nakayama, Naofumi Bunya, Jun Kataoka, Yusuke Endo, Takaharu Itami, Taku Hirokawa, Chihiro Sugita, Hirotaka Takeshima, Airi Takemoto, Miyako Kyogoku, Junki Koike, Shigeki Fujitani, Francesco Mojoli, Taku Miyasho
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	SpringerOpen 2025-10-01
Serie:	Intensive Care Medicine Experimental
Soggetti:	Breath stacking Spontaneous effort Ventilator-induced lung injury Volume-controlled ventilation Pressure-controlled ventilation Patient–ventilator interaction
Accesso online:	https://doi.org/10.1186/s40635-025-00821-0
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