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Let-7 Represses Carcinogenesis and a Stem Cell Phenotype in the Intestine via Regulation of Hmga2.

Let-7 miRNAs comprise one of the largest and most highly expressed family of miRNAs among vertebrates, and is critical for promoting differentiation, regulating metabolism, inhibiting cellular proliferation, and repressing carcinogenesis in a variety of tissues. The large size of the Let-7 family of...

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Autors principals: Blair B Madison, Arjun N Jeganathan, Rei Mizuno, Monte M Winslow, Antoni Castells, Miriam Cuatrecasas, Anil K Rustgi
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2015-08-01
Col·lecció:PLoS Genetics
Accés en línia:http://europepmc.org/articles/PMC4526516?pdf=render
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