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Activation of Adenosine Triphosphate-Gated Purinergic 2 Receptor Channels by Transient Receptor Potential Vanilloid Subtype 4 in Cough Hypersensitivity

Background: Transient receptor potential vanilloid subtype 4 (TRPV4) is a Ca<sup>2+</sup>-permeable non-selective cation channel that is involved in the development of cough hypersensitivity. Purinergic 2 receptors (P2X) belong to a class of adenosine triphosphate (ATP)-gated non-selective cation ch...

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Main Authors: Wanzhen Li, Shengyuan Wang, Tongyangzi Zhang, Yiqing Zhu, Li Yu, Xianghuai Xu
Format: Artigo
Language:Inglês
Published: MDPI AG 2025-02-01
Series:Biomolecules
Subjects:
cough hypersensitivity
transient receptor potential vanilloid 4
adenosine triphosphate
purinergic receptors
signaling pathway
Online Access:https://www.mdpi.com/2218-273X/15/2/285
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