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Lack of Atorvastatin Effect on Monocyte Gene Expression and Inflammatory Markers in HIV-1- infected ART-suppressed Individuals at Risk of non-AIDS Comorbidities

Background: Many people living with HIV have persistent monocyte activation despite viral suppression by antiretroviral therapy (ART), which contributes to non-AIDS complications including neurocognitive and other disorders. Statins have immunomodulatory properties that might be beneficial by reduc...

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Guardat en:
Autors principals: Anjana Yadav, Andrew Kossenkov, Louise Showe, Sarah Ratcliffe, Grace Choi, Luis Montaner, Pablo Tebas, Pamela Shaw, Ronald Collman
Format: Artigo
Idioma:Inglês
Publicat: Case Western Reserve University 2021-08-01
Col·lecció:Pathogens and Immunity
Matèries:
HIV/AIDS;
Antiretroviral therapy;
Atorvastatin;
Monocyte;
Gene expression;
Cytokine;
Accés en línia:https://www.paijournal.com/index.php/paijournal/article/view/461
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