A mammalianized synthetic nitroreductase gene for high-level expression
<p>Abstract</p> <p>Background</p> <p>The nitroreductase/5-(azaridin-1-yl)-2,4-dinitrobenzamide (NTR/CB1954) enzyme/prodrug system is considered as a promising candidate for anti-cancer strategies by gene-directed enzyme prodrug therapy (GDEPT) and has recently entered clinical trials. It requires th...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2009-08-01
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| coleção: | BMC Cancer |
| Acesso em linha: | http://www.biomedcentral.com/1471-2407/9/301 |
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