Revealing the role of cancer-associated fibroblast senescence in prognosis and immune landscape in pancreatic cancer

Summary: Cancer-associated fibroblasts (CAFs) represent a major contributor to tumor growth. Cellular senescence is a state of cell-cycle arrest characterized by a pro-inflammatory phenotype. The potential impact of CAF senescence on tumor progression and the tumor microenvironment (TME) remains to...

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Главные авторы:	Luyao Liu, Hai Huang, Bin Cheng, Huaping Xie, Wang Peng, Haochen Cui, Jingwen Liang, Mengdie Cao, Yilei Yang, Wei Chen, Ronghua Wang, Yuchong Zhao
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Elsevier 2025-01-01
Серии:	iScience
Предметы:	Microenvironment Immune response Cancer
Online-ссылка:	http://www.sciencedirect.com/science/article/pii/S2589004224028396
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