Clustering molecular dynamics conformations of the CC’-loop of the PD-1 immuno-checkpoint receptor
Molecular mechanisms within the checkpoint receptor PD-1 are essential for its activation by PD-L1 as well as for blocking such an activation via checkpoint inhibitors. We use molecular dynamics to scrutinize patterns of atomic motion in PD-1 without a ligand. Molecular dynamics is performed for the...
Gardado en:
| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Association for the Advancement of Science (AAAS)
2023-01-01
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| Series: | Computational and Structural Biotechnology Journal |
| Assuntos: | |
| Acceso en liña: | http://www.sciencedirect.com/science/article/pii/S2001037023002386 |
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