Graphene oxide suppresses the growth and malignancy of glioblastoma stem cell-like spheroids via epigenetic mechanisms

Abstract Background Glioblastoma stem-like cells (GSCs) are hypothesized to contribute to self-renewal and therapeutic resistance in glioblastoma multiforme (GBM) tumors. Constituting only a small percentage of cancer cells, GSCs possess “stem-like”, tumor-initiating properties and display resistanc...

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Autori principali:	Xu Wang, Wenjuan Zhou, Xian Li, Jun Ren, Guangyu Ji, Jingyi Du, Wenyu Tian, Qian Liu, Aijun Hao
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2020-05-01
Serie:	Journal of Translational Medicine
Soggetti:	Graphene oxide Glioblastoma stem-like cells Epigenetics Cell differentiation
Accesso online:	http://link.springer.com/article/10.1186/s12967-020-02359-z
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