Enhancing radiotherapy in triple-negative breast cancer with hesperetin-induced ferroptosis via AURKA targeting nanocomposites

Abstract Triple-negative breast cancer (TNBC) is an aggressive cancer type that lacks targeted treatment options. Ferroptosis, a novel therapeutic strategy, induces cell death by disrupting the oxidative-reductive balance. Hesperetin, a potential TNBC therapeutic drug, has unidentified regulatory ta...

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Auteurs principaux:	Yang Guo, Huan Wang, Xinlei Wang, Keyan Chen, Liang Feng
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2024-11-01
Collection:	Journal of Nanobiotechnology
Sujets:	Triple-negative breast cancer Ferroptosis Hesperetin AURKA Redox homeostasis Radiotherapy efficacy
Accès en ligne:	https://doi.org/10.1186/s12951-024-02987-3
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