CD3+RUNX3+ lymphocyte density; an independent prognostic factor in colon and lung adenocarcinoma but not in lung squamous cell carcinoma

Abstract RUNX3, an important regulator of T-cell differentiation plays a crucial role in activation and maintenance of various T-cells including cytotoxic-, helper- and memory-cells. Former studies have highlighted RUNX3 as a prognostic factor across several cancer types, but few have studied its ce...

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Principais autores:	Thomas K. Kilvaer, Dagny Førde, Erna-Elise Paulsen, Mona Irene Pedersen, Ana Paola Lombardi, Mehrdad Rakaee, Hallgeir Selven, Tom Donnem, Lill-Tove Rasmussen Busund, Sigve Andersen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2026-02-01
coleção:	Scientific Reports
Assuntos:	NSCLC Lung cancer Colon cancer CRC RUNX3 CD3
Acesso em linha:	https://doi.org/10.1038/s41598-026-38765-4
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