Dysregulated circRNA–miRNA–mRNA networks reveal stage-specific mRNA expression changes in Parkinson’s disease

Abstract Parkinson’s disease (PD) is a progressive neurodegenerative disorder marked by the loss of dopaminergic neurons and widespread transcriptomic dysregulation across disease stages. Patients commonly exhibit motor symptoms such as tremors, rigidity, and bradykinesia, alongside non-motor sympto...

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Bibliografische gegevens

Hoofdauteurs:	Yulan Gao, Konii Takenaka, Kristina Santucci, Grace Lindner, Si-Mei Xu, Yuning Cheng, Michael Janitz
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	BMC 2025-12-01
Reeks:	Molecular Brain
Onderwerpen:	Parkinson’s disease circRNA-miRNA-mRNA Uniquely expressed circRNAs RNA-seq circPRDM2 circHSH2D
Online toegang:	https://doi.org/10.1186/s13041-025-01262-2
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