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Make or break - PEDS1 and AGMO orchestrate ether lipid homeostasis in human adipocytes and are associated with blood lipid profiles

Abstract Background Obesity and its associated sequelae have become a major global health concern. While ester-linked lipids are well-established regulators of adipocyte function and energy storage. Emerging evidence from cohort studies suggests that ether-linked lipid levels are also altered during...

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Principais autores: Sabrina Sailer, Tina Deutinger, Susanne Lobenwein, Katharina Lackner, Stephan Geley, Georg Golderer, Ernst R. Werner, Markus A. Keller, Christian Ploner, Katrin Watschinger
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2026-01-01
Serier:Journal of Translational Medicine
Fag:
Ether lipid metabolism
Adipose tissue
Lipidomics
Lipoprotein particles
Plasmanylethanolamine desaturase
Alkylglycerol monooxygenase
Online adgang:https://doi.org/10.1186/s12967-026-07728-8
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