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RHAMM deficiency disrupts folliculogenesis resulting in female hypofertility

The postnatal mammalian ovary contains the primary follicles, each comprising an immature oocyte surrounded by a layer of somatic granulosa cells. Oocytes reach meiotic and developmental competence via folliculogenesis. During this process, the granulosa cells proliferate massively around the oocyte...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Huaibiao Li, Jürgen Moll, Anne Winkler, Lucien Frappart, Stéphane Brunet, Jana Hamann, Torsten Kroll, Marie-Hélène Verlhac, Heike Heuer, Peter Herrlich, Aspasia Ploubidou
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists 2015-03-01
Schriftenreihe:Biology Open
Schlagworte:
Gametogenesis
Folliculogenesis
Hypofertility
Spindle
RHAMM
Oriented mitosis
Centrosome
Online-Zugang:http://bio.biologists.org/content/4/4/562
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