Competition between skin antimicrobial peptides and commensal bacteria in type 2 inflammation enables survival of S. aureus

Summary: During inflammation, the skin deploys antimicrobial peptides (AMPs) yet during allergic inflammation it becomes more susceptible to Staphylococcus aureus. To understand this contradiction, single-cell sequencing of Il4ra−/− mice combined with skin microbiome analysis reveals that lower prod...

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Detalhes bibliográficos

Principais autores:	Teruaki Nakatsuji, Samantha L. Brinton, Kellen J. Cavagnero, Alan M. O’Neill, Yang Chen, Tatsuya Dokoshi, Anna M. Butcher, Olive C. Osuoji, Faiza Shafiq, Josh L. Espinoza, Christopher L. Dupont, Tissa R. Hata, Richard L. Gallo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2023-05-01
coleção:	Cell Reports
Assuntos:	CP: Microbiology CP: Immunology
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2211124723005053
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