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Triazine herbicide prometryn alters epoxide hydrolase activity and increases cytochrome P450 metabolites in murine livers via lipidomic profiling

Abstract Oxylipins are a group of bioactive fatty acid metabolites generated via enzymatic oxygenation. They are notably involved in inflammation, pain, vascular tone, hemostasis, thrombosis, immunity, and coagulation. Oxylipins have become the focus of therapeutic intervention since they are implic...

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Principais autores: Rasheed O. Sule, Christophe Morisseau, Jun Yang, Bruce D. Hammock, Aldrin V. Gomes
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2024-08-01
Serier:Scientific Reports
Fag:
Prometryn
Lipidomics
Oxylipins
Oxidative stress
Inflammation
Liver
Online adgang:https://doi.org/10.1038/s41598-024-69557-3
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