Suppression of Nucleotide Metabolism Underlies the Establishment and Maintenance of Oncogene-Induced Senescence

Oncogene-induced senescence is characterized by a stable cell growth arrest, thus providing a tumor suppression mechanism. However, the underlying mechanisms for this phenomenon remain unknown. Here, we show that a decrease in deoxyribonucleotide triphosphate (dNTP) levels underlies oncogene-induced...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Katherine M. Aird, Gao Zhang, Hua Li, Zhigang Tu, Benjamin G. Bitler, Azat Garipov, Hong Wu, Zhi Wei, Stephan N. Wagner, Meenhard Herlyn, Rugang Zhang
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Elsevier 2013-04-01
Sarja:	Cell Reports
Linkit:	http://www.sciencedirect.com/science/article/pii/S2211124713001113
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