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Apoptosis Induced via Gamma Delta T Cell Antigen Receptor “Blocking” Antibodies: A Cautionary Tale

Mechanistic studies contribute greatly to our understanding of γδ T cell (γδTc) biology, aiding development of these cells as immunotherapeutic agents. The antibody blocking assay is an accepted method to determine the receptors involved in γδTc killing of tumor targets. Effectors and/or targets are...

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Autors principals: Indrani Dutta, Lynne-Marie Postovit, Gabrielle M. Siegers
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017-06-01
Col·lecció:Frontiers in Immunology
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Accés en línia:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00776/full
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