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Centrosomal P4.1-associated protein is a novel regulator of ESCRT pathway function during endosome maturation

Summary: Previously, we reported that centrosomal P4.1-associated protein (CPAP/CENPJ/SAS-4) positively regulates multivesicular body (MVB) biogenesis and endocytic vesicular transport (EVT). Here, we show that CPAP is required for Rab5-to-Rab7 conversion and that the recruitment of TSG101 to early...

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Principais autores: Radhika Gudi, Chenthamarakshan Vasu
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2026-02-01
Serier:iScience
Fag:
Molecular biology
Molecular interaction
Molecular network
Online adgang:http://www.sciencedirect.com/science/article/pii/S2589004226000349
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