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Susceptibility of epithelial cells cultured from different regions of human cervix to HPV16-induced immortalization.

Persistent infection with high-risk human papillomavirus (HPV) is a major risk factor for cervical cancer. Greater than 90% of these cancers originate in the cervical transformation zone (TZ), a narrow region of metaplastic squamous epithelium that develops at the squamocolumnar junction between the...

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Autors principals: Han Deng, Eric Hillpot, Philomina Yeboah, Sumona Mondal, Craig D Woodworth
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2018-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC6019754?pdf=render
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