Non-coding variants impact cis-regulatory coordination in a cell type-specific manner

Abstract Background Interactions among cis-regulatory elements (CREs) play a crucial role in gene regulation. Various approaches have been developed to map these interactions genome-wide, including those relying on interindividual epigenomic variation to identify groups of covariable regulatory elem...

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Hlavní autoři:	Olga Pushkarev, Guido van Mierlo, Judith Franziska Kribelbauer, Wouter Saelens, Vincent Gardeux, Bart Deplancke
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2024-07-01
Edice:	Genome Biology
Témata:	Cis-regulatory interactions Epigenomics Genome-wide association studies Quantitative trait loci Gene regulation
On-line přístup:	https://doi.org/10.1186/s13059-024-03333-4
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