PANAMA-enabled high-sensitivity dual nanoflow LC-MS metabolomics and proteomics analysis

Summary: High-sensitivity nanoflow liquid chromatography (nLC) is seldom employed in untargeted metabolomics because current sample preparation techniques are inefficient at preventing nanocapillary column performance degradation. Here, we describe an nLC-based tandem mass spectrometry workflow that...

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Autori principali:	Weiwei Lin, Fatemeh Mousavi, Benjamin C. Blum, Christian F. Heckendorf, Matthew Lawton, Noah Lampl, Ryan Hekman, Hongbo Guo, Mark McComb, Andrew Emili
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2024-07-01
Serie:	Cell Reports: Methods
Soggetti:	CP: biotechnology CP: metabolism
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2667237524001590
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