Polyfunctional T cells and unique cytokine clusters imprint the anti rAAV2/rAAV9 vector immune response

Polyfunctional T cells programmed to perform activities such as degranulation of lytic enzymes and simultaneous production of multiple cytokines are associated with more effective control of viral infections. Immune responses to recombinant adeno-associated virus (rAAV) vector delivery systems can c...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Stephan J. Holtkamp, Florian R. Lagoda, Adam Lister, Pradeep Harish, Ulrike Kleymann, Theresa Pesch, Chai Fen Soon, Munir Pirmohamed, Dean Naisbitt, Mark Trautwein
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Frontiers Media S.A. 2024-11-01
Sarja:	Frontiers in Immunology
Aiheet:	adeno-associated virus immunogenicity CD4 T cell immunity gene therapy polyfunctional T cells T cell secretome
Linkit:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1450524/full
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