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Neospora caninum as delivery vehicle for anti-PD-L1 scFv-Fc: A novel approach for cancer immunotherapy

Neospora caninum, a potential anticancer agent able to reactivate the immune response within the tumor microenvironment (TME), has recently shown enhanced immunomodulatory properties in different tumor models when armed with the cytokine, Il-15. In the current area of combination immunotherapy strat...

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Principais autores: Clément Riviere, Muna Aljieli, Marie-Noëlle Mévélec, Louis Lantier, Fanny Boursin, Laurie Lajoie, Céline Ducournau, Stéphanie Germon, Nathalie Moiré, Isabelle Dimier-Poisson, Nicolas Aubrey, Anne di Tommaso
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2025-06-01
Colecção:Molecular Therapy: Oncology
Assuntos:
MT: Regular Issue
Neospora caninum
antibody fragment
scFv-Fc
secretion
cancer immunotherapy
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2950329925000372
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