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Transient transfection using 222 nm far UV-C irradiation

Abstract Ultraviolet (UV) light is never used for gene transfer because it damages DNA and harms cellular and plasmid DNA. A light source selectively radiating Far UV-C (F-UV) light causes less DNA damage. We investigated potential introduction of plasmids into cells by irradiating them with F-UV li...

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Principais autores: Mane Nishimura, Yuki Shimizu, Tomohiro Fujii, Yu Okada, Takeshi Yamamoto, Yoshimasa Ogawa, Toru Koi, Yutaka Suehiro, Takahiro Yamasaki, Jun Nishikawa
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2025-05-01
Serier:Scientific Reports
Fag:
Far UV-C
222 nm
Transfection
Deep-ultraviolet
DNA damage
Online adgang:https://doi.org/10.1038/s41598-025-00477-6
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