Investigating the potential impact of PCSK9-inhibitors on mood disorders using eQTL-based Mendelian randomization.
Prescription of PCSK9-inhibitors has increased in recent years but not much is known about its off-target effects. PCSK9-expression is evident in non-hepatic tissues, notably the brain, and genetic variation in the PCSK9 locus has recently been shown to be associated with mood disorder-related trait...
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| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science (PLoS)
2022-01-01
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| coleção: | PLoS ONE |
| Acesso em linha: | https://doi.org/10.1371/journal.pone.0279381 |
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