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Neoadjuvant tislelizumab with afatinib for locally advanced head and neck squamous cell carcinoma (neoCHANCE-1): a phase 2 clinical trial

Abstract Despite receiving standard treatments, patients with locally advanced head and neck squamous cell carcinoma (LA-HNSCC) often still face significant risks of disease recurrence or metastasis. In this phase II neoCHANCE-1 study (NCT05517330), we evaluated the efficacy and safety of the dual-t...

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Autors principals: Zhi-gong Wei, Hui-jiao Chen, De-juan Wang, Zheng Jiang, Yi-yan Pei, Le-yu Li, Feng Wang, Jing Jin, Zhe-ran Liu, Fei Chen, Jun Liu, Xing-chen Peng
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2025-10-01
Col·lecció:Nature Communications
Accés en línia:https://doi.org/10.1038/s41467-025-63978-y
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