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T-shaped alignments integrating HIV-1 near full-length genome and partial pol sequences can improve phylogenetic inference of transmission clusters.

Molecular epidemiology and HIV-1 transmission networks reconstruction can provide insights into transmission dynamics and inform public health strategies. Long HIV sequences, such as near full-length (nFL) genomes, can improve the accuracy of phylogenetic inference. However, relatively short pol seq...

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Autors principals: August Guang, Casey W Dunn, Vlad Novitsky, Mark Howison, Rami Kantor
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2025-11-01
Col·lecció:PLoS Computational Biology
Accés en línia:https://doi.org/10.1371/journal.pcbi.1013676
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