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Affordable drug resistance genotyping of HIV-1 reverse transcriptase, protease and integrase genes, for resource limited settings

Abstract Background As use of dolutegravir (DTG) becomes more common in resource limited settings (RLS), the demand for integrase resistance testing is increasing. Affordable methods for genotyping all relevant HIV-1 pol genes (i.e., protease (PR), reverse transcriptase (RT) and integrase (IN)) are...

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Principais autores: Sontaga Manyana, Melendhran Pillay, Lilishia Gounder, Aabida Khan, Pravi Moodley, Kogieleum Naidoo, Benjamin Chimukangara
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2023-02-01
coleção:AIDS Research and Therapy
Assuntos:
HIV-1
Pol gene
Affordable genotypic testing
Drug resistance
Resource limited settings
Primary integrase resistance
Acesso em linha:https://doi.org/10.1186/s12981-023-00505-3
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