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Restrictive versus standard intravenous fluid therapy and NTproBNP in ICU patients with septic shock – a sub-study of the randomised CLASSIC trial

Abstract Background Cardiac dysfunction is common in septic shock and may be influenced by intravenous (IV) fluid therapy. We aimed to investigate the effects of restrictive versus standard IV fluid therapy on plasma N-terminal pro B-type natriuretic peptide (NTproBNP), a marker of cardiac dysfuncti...

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Principais autores: Jens Christensen, Praleene Sivapalan, Tine Sylvest Meyhoff, Hans Järnbert-Pettersson, Anders Perner, Morten Hylander Møller, Theis Lange, Peter Buhl Hjortrup, Eva Joelsson-Alm, Sandra Jonmarker, Fredric Sjöberg, Johan Mårtensson, Anna Håkansson Gladh, Maria Cronhjort
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2026-04-01
coleção:BMC Anesthesiology
Assuntos:
Septic shock
Cardiac dysfunction
Fluid therapy
NTproBNP
Randomised controlled trial
Acesso em linha:https://doi.org/10.1186/s12871-026-03836-6
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