Hedgehog activation promotes osteogenic fates of growth plate resting zone chondrocytes through transient clonal competency

The resting zone of the postnatal growth plate is organized by slow-cycling chondrocytes expressing parathyroid hormone-related protein (PTHrP), which include a subgroup of skeletal stem cells that contribute to the formation of columnar chondrocytes. The PTHrP–Indian hedgehog feedback regulation is...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Shion Orikasa, Yuki Matsushita, Hiroaki Manabe, Michael Fogge, Zachary Lee, Koji Mizuhashi, Naoko Sakagami, Wanida Ono, Noriaki Ono
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical investigation 2024-01-01
Colección:JCI Insight
Materias:
Bone biology
Stem cells
Acceso en línea:https://doi.org/10.1172/jci.insight.165619
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares