HIV induces production of IL-18 from intestinal epithelial cells that increases intestinal permeability and microbial translocation.
Interleukin-18 (IL-18) is a pleiotropic cytokine of the IL-1 family with multiple context dependent functions. We and others have shown that HIV infection is accompanied by increased circulating levels of IL-18 along with decreased levels of its antagonist, Interleukin-18 Binding Protein (IL-18BP)....
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| Główni autorzy: | , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Public Library of Science (PLoS)
2018-01-01
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| Seria: | PLoS ONE |
| Dostęp online: | http://europepmc.org/articles/PMC5877838?pdf=render |
| Etykiety: |
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