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Preparation, characterization, in vitro drug release and anti-inflammatory of thymoquinone-loaded chitosan nanocomposite

In this study, we formulated Thymoquinone-loaded nanocomposites (TQ-NCs) using high-pressure homogenizer without sodium tripolyphosphate. The TQ-NCs were characterized and their anti-inflammatory determined by the response of the LPS-stimulated macrophage RAW 264.7 cells in the production of nitric...

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Principais autores: Mothanna Sadiq Al-Qubaisi, Ashwaq Shakir Al-Abboodi, Fatah H. Alhassan, Samer Hussein-Al-Ali, Moayad Husein Flaifel, Eltayeb E.M. Eid, Hussah Abdullah Alshwyeh, Mohd Zobir Hussein, Sulaiman Mohammed Alnasser, Mohammed Ibrahim Saeed, Abdullah Rasedee, Wisam Nabeel Ibrahim
Format: Artigo
Sprog:Inglês
Udgivet: Springer 2022-04-01
Serier:Saudi Pharmaceutical Journal
Fag:
Thymoquinone
Nanocomposite
High-pressure homogenizer
Drug release
RAW 264.7 cells
Inflammatory mediators
Online adgang:http://www.sciencedirect.com/science/article/pii/S1319016422000408
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