Functional network analysis in hepatolithiasis: identifying novel therapeutic targets through whole-exome sequencing

Background Hepatolithiasis (HL) is a prevalent condition in hepatobiliary surgery, often complicated by hepatatrophia. This study aimed to identify gene mutations in HL specimens with hepatatrophia and construct a mutation landscape using whole-exome sequencing (WES). Methods Genetic variants and co...

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Detalhes bibliográficos

Principais autores:	Dan Tang, Xuanyu Gu, Dan Liu, Jiali Yang, Lijin Zhao
Formato:	Artigo
Idioma:	Inglês
Publicado em:	PeerJ Inc. 2026-04-01
coleção:	PeerJ
Assuntos:	Hepatolithiasis Hepatatrophia Whole-exome sequencing Mutation analysis
Acesso em linha:	https://peerj.com/articles/21059.pdf
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