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Evaluation of the Ligand‐Independent Activation of a VHH‐Based Anti‐CD19 SynNotch Receptor by Dual‐Luciferase Assay

ABSTRACT Ligand‐independent activation poses a significant challenge for synthetic receptors, limiting their dynamic range. Given the difficulties and inconsistencies in evaluating this crucial aspect in many studies, we utilized a dual‐luciferase assay to assess the background activity of the SynNo...

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Detalles Bibliográficos
Principais autores: Yasaman Asaadi, Fatemeh Rahbarizadeh
Formato: Artigo
Idioma:Inglês
Publicado: Wiley-VCH 2025-12-01
Series:Analytical Science Advances
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Acceso en liña:https://doi.org/10.1002/ansa.70046
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