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A precision medicine classification for treatment of acute myeloid leukemia in older patients

Abstract Background Older patients (≥ 60 years) with acute myeloid leukemia (AML) often have multiple, sequentially acquired, somatic mutations that drive leukemogenesis and are associated with poor outcome. Beat AML is a Leukemia and Lymphoma Society-sponsored, multicenter umbrella study that algor...

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Автори: Alice S. Mims, Jessica Kohlschmidt, Uma Borate, James S. Blachly, Shelley Orwick, Ann-Kathrin Eisfeld, Dimitrios Papaioannou, Deedra Nicolet, Krzysztof Mrόzek, Eytan Stein, Bhavana Bhatnagar, Richard M. Stone, Jonathan E. Kolitz, Eunice S. Wang, Bayard L. Powell, Amy Burd, Ross L. Levine, Brian J. Druker, Clara D. Bloomfield, John C. Byrd
Формат: Artigo
Мова:Inglês
Опубліковано: BMC 2021-06-01
Серія:Journal of Hematology & Oncology
Предмети:
Acute myeloid leukemia
Mutation
Cytogenetics
Precision medicine
Outcome
Онлайн доступ:https://doi.org/10.1186/s13045-021-01110-5
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