The role of T cell trafficking in CTLA-4 blockade-induced gut immunopathology
Abstract Background Immune checkpoint inhibitor (ICPI) can augment the anti-tumour response by blocking negative immunoregulators with monoclonal antibodies. The anti-cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) antibody is the first ICPI which has shown remarkable benefits in the clinical t...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2020-03-01
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| coleção: | BMC Biology |
| Assuntos: | |
| Acesso em linha: | http://link.springer.com/article/10.1186/s12915-020-00765-9 |
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