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Synaptic mechanisms modulate the spatiotemporal dynamics of striatal direct pathway neurons and motor output

Striatal spiny-projection neurons (SPNs) integrate glutamatergic inputs from the motor cortex and thalamus with neuromodulatory signals to regulate motor output. In vivo Ca2+ imaging has demonstrated that spatially overlapping ensembles of direct and indirect pathway SPNs (dSPNs, iSPNs) are co-activ...

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Auteurs principaux: John J Marshall, Jian Xu, Nai-Hsing Yeh, Seongsik Yun, Toshihiro Nomura, John N Armstrong, Jones Parker, Anis Contractor
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications Ltd 2026-01-01
Collection:eLife
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Accès en ligne:https://elifesciences.org/articles/98122
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