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Distinct cellular signatures in aplastic and intermittent phenotypes of immune effector cell-associated hematotoxicity

Abstract Bone marrow toxicity, or immune effector cell-associated hematotoxicity (ICAHT), is a notable complication of CAR T-cell therapy, characterized by persistent cytopenia’s and typically classified into three phenotypes: transient, intermittent and aplastic. This study aimed to characterize th...

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Principais autores: Ben Varon, Amir Grau, Noga Setter Marco, Anwar Khatib, Tsofia Levi, Riva Fineman, Inna Tzoran, Nivin Mustafa, Tsila Zuckerman, Netanel A. Horowitz, Noa Lavi, Rostislav Novak, Ofrat Beyar-Katz
Format: Artigo
Sprog:Inglês
Udgivet: Springer 2026-04-01
Serier:Annals of Hematology
Fag:
ICAHT
Aplastic ICAHT
Intermittent ICAHT
CRS
Online adgang:https://doi.org/10.1007/s00277-026-06993-3
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