Beneficial mechanisms of dimethyl fumarate in autoimmune uveitis: insights from single-cell RNA sequencing

Abstract Background Dimethyl fumarate (DMF) is a fumaric acid ester that exhibits immunoregulatory and anti-inflammatory properties. However, the function of DMF in autoimmune uveitis (AU) is incompletely understood, and studies comprehensively exploring the impact of DMF on immune cells are still l...

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Principais autores:	Lei Zhu, He Li, Xuening Peng, Zhaohuai Li, Sichen Zhao, Dongting Wu, Jialing Chen, Si Li, Renbing Jia, Zuohong Li, Wenru Su
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2024-04-01
Series:	Journal of Neuroinflammation
Assuntos:	Autoimmune uveitis Dimethyl fumarate PIM1 CXCR4 Single-cell RNA sequencing
Acceso en liña:	https://doi.org/10.1186/s12974-024-03096-6
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