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Impairment in stimulus-response learning as a cognitive biomarker in a model of synucleinopathy

Abstract Translating findings from preclinical assessments of cognitive function relevant to synucleinopathies into successful clinical trials poses significant challenges. In this study, we examined the effectiveness of human-relevant touchscreen cognitive assessments in detecting the impact of α-s...

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Hlavní autoři: Oren Princz-Lebel, Anoosha Attaran, Rodrigo Sandoval Contreras, Vladislav Novikov, Samina Panjwani, Anthony Chu, Cherisse Tan, Claire A. Lemieux, Miguel Skirzewski, Meira M. F. Machado, Joel C. Watts, Jacob A. McPhail, Ariel Louwrier, Vania F. Prado, Lisa M. Saksida, Marco A. M. Prado, Timothy J. Bussey
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2026-01-01
Edice:Translational Psychiatry
On-line přístup:https://doi.org/10.1038/s41398-025-03795-5
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