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Evolocumab prevents atrial fibrillation in rheumatoid arthritis rats through restraint of PCSK9 induced atrial remodeling

Introduction: Proprotein convertase subtilisin/kexin type 9 (PCSK9) is implicated in the pathogenesis and progression of autoimmune disease. Patients with rheumatoid arthritis (RA) are at high risk of developing atrial fibrillation (AF), while whether PCSK9 is involved in the onset of AF among RA pa...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Xuejie Han, Yunlong Gao, Meijiao He, Yingchun Luo, Ying Wei, Yu Duan, Song Zhang, Hui Yu, Jiuxu Kan, Te Hou, Yun Zhang, Yue Li
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2024-07-01
Schriftenreihe:Journal of Advanced Research
Schlagworte:
Rheumatoid arthritis
Atrial fibrillation
PCSK9
Evolocumab
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2090123223002564
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