Redox Regulation of Phosphatase and Tensin Homolog by Bicarbonate and Hydrogen Peroxide: Implication of Peroxymonocarbonate in Cell Signaling

Phosphatase and tensin homolog (PTEN) is a negative regulator of the phosphoinositide 3-kinases/protein kinase B (PI3K/AKT) signaling pathway. Notably, its active site contains a cysteine residue that is susceptible to oxidation by hydrogen peroxide (H₂O₂). This oxidation inhib...

Popoln opis

Bibliografske podrobnosti

Principais autores:	Vu Hoang Trinh, Jin-Myung Choi, Thang Nguyen Huu, Dhiraj Kumar Sah, Hyun-Joong Yoon, Sang-Chul Park, Yu-Seok Jung, Young-Keun Ahn, Kun-Ho Lee, Seung-Rock Lee
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2024-04-01
Serija:	Antioxidants
Teme:	PTEN redox regulation cell signaling H<sub>2</sub>O<sub>2</sub> bicarbonate peroxymonocarbonate carbonic anhydrase
Online dostop:	https://www.mdpi.com/2076-3921/13/4/473
Oznake:	Označite Brez oznak, prvi označite!