A protein sequence-based deep transfer learning framework for identifying human proteome-wide deubiquitinase-substrate interactions
Abstract Protein ubiquitination regulates a wide range of cellular processes. The degree of protein ubiquitination is determined by the delicate balance between ubiquitin ligase (E3)-mediated ubiquitination and deubiquitinase (DUB)-mediated deubiquitination. In comparison to the E3-substrate interac...
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| Hlavní autoři: | , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Portfolio
2024-05-01
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| Edice: | Nature Communications |
| On-line přístup: | https://doi.org/10.1038/s41467-024-48446-3 |
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