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Improved Local Anesthesia at Inflamed Tissue Using the Association of Articaine and Copaiba Oil in Avocado Butter Nanostructured Lipid Carriers

Unsuccessful anesthesia often occurs under an inflammatory tissue environment, making dentistry treatment extremely painful and challenging. Articaine (ATC) is a local anesthetic used at high (4%) concentrations. Since nanopharmaceutical formulations may improve the pharmacokinetics and pharmacodyna...

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Principais autores: Gustavo Henrique Rodrigues da Silva, Julia Borges Paes Lemes, Gabriela Geronimo, Fabíola Vieira de Carvalho, Talita Cesarim Mendonça, Kauê Franco Malange, Fernando Freitas de Lima, Márcia Cristina Breitkreitz, Carlos Amilcar Parada, Teresa Dalla Costa, Eneida de Paula
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-04-01
Serier:Pharmaceuticals
Fag:
drug delivery systems
nanostructured lipid carriers
inflammation
local anesthetics
articaine
Online adgang:https://www.mdpi.com/1424-8247/16/4/546
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